· Several studies have found cetirizine (Zyrtec) to be more effective than fexofenadine (Allegra) at relieving symptoms of allergic rhinitis and urticaria, and it appears to have a longer duration of action. · Key takeaways: Zyrtec (cetirizine), Claritin (loratadine), and Allegra (fexofenadine) are over-the-counter (OTC) antihistamines used to treat allergies. Overall, they work similarly well, but you may find that one works better for you. · Learn the differences between Allegra and Zyrtec, two over-the-counter allergy medications that block histamine. Compare their forms, dosage, side effects, interactions, and warnings. · Learn how these antihistamines differ in terms of speed, dosage, side effects, and pregnancy safety. Find out which one is best for your allergy symptoms and how to avoid interactions. · Allegra and Zyrtec are popular allergy medicines. Compare side effects, effectiveness, and dosages to decide which antihistamine may work best for your symptoms. Both ZYRTEC ® and Allegra ® help treat common allergy symptoms, but ZYRTEC ® offers an allergy app that can help you manage your allergy symptoms. Explore our chart below to compare Allegra ® vs. ZYRTEC ® to help you decide if ZYRTEC ® or Allegra ® is the right allergy medicine for you. Is Zyrtec stronger than Allegra?Is Zyrtec stronger than Allegra? Score5/5 Allegra works within two hours and Zyrtec works within one hour. Several studies have found cetirizine (Zyrtec) to be more effective than fexofenadine(Allegra) at relieving symptoms of allergic rhinitis and urticaria, and it appears to have a longer duration of action. Read more Allegra Vs ZyrtecIs there a difference between Claritin and Zyrtec?Zyrtec is piperazine chemically whereas Claritin is piperidine chemically. Zyrtec does not have active metabolite while Claritin has an active metabolite; Zyrtec is available as tablet and syrup whereas Claritin is available as tablet, syrup, and suspension. Zyrtec available strength is 5-10mg while Claritin available strength is 10mg. ConclusionIs Xyzal better than Zyrtec?So, it is often thought that these medications have the same effects and risks. A study compared levocetirizine (Xyzal) to cetirizine (Zyrtec) in children with seasonal allergies. Both medications were more effective than placebo (dummy pill) at improving symptoms. But cetirizine appeared to work better than levocetirizine. · Two of the most popular and effective choices are Allegra and Zyrtec. But which one is truly better? The answer, like many things in medicine, is not a simple one. It depends entirely on your unique body, your specific allergy symptoms, and your lifestyle. This article will serve as your detailed guide. · Allegra and Zyrtec are popular allergy medicines. Compare side effects, effectiveness, and dosages to decide which antihistamine may work best for your symptoms. Both ZYRTEC ® and Allegra ® help treat common allergy symptoms, but ZYRTEC ® offers an allergy app that can help you manage your allergy symptoms. Explore our chart below to compare Allegra ® vs. ZYRTEC ® to help you decide if ZYRTEC ® or Allegra ® is the right allergy medicine for you. · Two of the most popular and effective choices are Allegra and Zyrtec. But which one is truly better? The answer, like many things in medicine, is not a simple one. It depends entirely on your unique body, your specific allergy symptoms, and your lifestyle. This article will serve as your detailed guide.